
50/50
Adam is a 27 year old writer of radio programs and is diagnosed with a rare form of spinal cancer. With the help of his best friend, his mother, and a young therapist at the cancer center, Adam learns what and who the most important things in his life are.
Despite its modest budget of $8.0M, 50/50 became a solid performer, earning $39.2M worldwide—a 390% return. The film's unique voice resonated with audiences, illustrating how strong storytelling can transcend budget limitations.
12 wins & 28 nominations
Plot Structure
Story beats plotted across runtime


Narrative Arc
Emotional journey through the story's key moments
Story Circle
Blueprint 15-beat structure
Arcplot Score Breakdown
Weighted: Precision (70%) + Arc (15%) + Theme (15%)
50/50 (2011) exemplifies strategically placed narrative architecture, characteristic of Jonathan Levine's storytelling approach. This structural analysis examines how the film's 12-point plot structure maps to proven narrative frameworks across 1 hour and 40 minutes. With an Arcplot score of 7.0, the film balances conventional beats with creative variation.
Characters
Cast & narrative archetypes

Adam Lerner

Kyle Hirons

Katherine McKay

Rachael Lerner

Diane Lerner
Main Cast & Characters
Adam Lerner
Played by Joseph Gordon-Levitt
A 27-year-old public radio journalist diagnosed with a rare spinal cancer who must navigate treatment while maintaining relationships.
Kyle Hirons
Played by Seth Rogen
Adam's best friend and coworker, a brash and crude but loyal companion who helps him through his cancer journey.
Katherine McKay
Played by Anna Kendrick
Adam's inexperienced but empathetic therapist who develops a deep connection with him during his treatment.
Rachael Lerner
Played by Bryce Dallas Howard
Adam's girlfriend who struggles to cope with his cancer diagnosis and ultimately proves unable to handle the situation.
Diane Lerner
Played by Anjelica Huston
Adam's overbearing but well-meaning mother who is already caring for her husband with Alzheimer's.
Structural Analysis
The Status Quo at 1 minutes (1% through the runtime) establishes Adam jogs through Seattle streets, crossing against traffic lights and narrowly avoiding cars - establishing his cautious, rule-following personality and the irony that he'll face a threat he cannot control.. Notably, this early placement immediately immerses viewers in the story world.
The inciting incident occurs at 12 minutes when Dr. Ross tells Adam he has a malignant schwannoma neurofibrosarcoma on his spine - a rare cancer with a 50/50 survival rate. Adam is stunned and his controlled world shatters.. At 12% through the film, this Disruption aligns precisely with traditional story structure. This beat shifts the emotional landscape, launching the protagonist into the central conflict.
The First Threshold at 24 minutes marks the transition into Act II, occurring at 24% of the runtime. This demonstrates the protagonist's commitment to Adam begins chemotherapy, actively choosing to fight the cancer. He enters the treatment center, shaves his head preemptively, and commits to the grueling process ahead., moving from reaction to action.
At 51 minutes, the Midpoint arrives at 51% of the runtime—precisely centered, creating perfect narrative symmetry. Significantly, this crucial beat Adam discovers Rachael has been cheating on him. Kyle reveals he saw her with another man. This false defeat compounds Adam's crisis - not only is his body betraying him, but so is his girlfriend. The stakes raise dramatically., fundamentally raising what's at risk. The emotional intensity shifts, dividing the narrative into clear before-and-after phases.
The Collapse moment at 75 minutes (75% through) represents the emotional nadir. Here, Adam learns the chemotherapy hasn't worked and he needs immediate surgery with only a 50/50 chance of survival. His chemo buddy Mitch also dies. Death is no longer abstract - it's imminent and real., reveals the protagonist at their lowest point. This beat's placement in the final quarter sets up the climactic reversal.
The Synthesis at 80 minutes initiates the final act resolution at 80% of the runtime. Adam is prepped for surgery surrounded by Kyle and his mother. He confronts his mortality in the operating room. Post-surgery, he recovers, reconnects with Katherine romantically, and learns to live with uncertainty rather than control., demonstrating the transformation achieved throughout the journey.
Emotional Journey
50/50's emotional architecture traces a deliberate progression across 12 carefully calibrated beats.
Narrative Framework
This structural analysis employs structural analysis methodology used to understand storytelling architecture. By mapping 50/50 against these established plot points, we can identify how Jonathan Levine utilizes or subverts traditional narrative conventions. The plot point approach reveals not only adherence to structural principles but also creative choices that distinguish 50/50 within the comedy genre.
Jonathan Levine's Structural Approach
Among the 5 Jonathan Levine films analyzed on Arcplot, the average structural score is 7.3, reflecting strong command of classical structure. 50/50 takes a more unconventional approach compared to the director's typical style. For comparative analysis, explore the complete Jonathan Levine filmography.
Comparative Analysis
Additional comedy films include The Ministry of Ungentlemanly Warfare, The Bad Guys and Lake Placid. For more Jonathan Levine analyses, see Warm Bodies, Snatched and Long Shot.
Plot Points by Act
Act I
SetupStatus Quo
Adam jogs through Seattle streets, crossing against traffic lights and narrowly avoiding cars - establishing his cautious, rule-following personality and the irony that he'll face a threat he cannot control.
Theme
Kyle tells Adam "You can't get diseases from lakes. The lake is sterile" while encouraging him to be more spontaneous - establishing the theme about control, risk, and how you can do everything right and still face catastrophe.
Worldbuilding
Establishment of Adam's ordinary world: his job at Seattle public radio, his controlling girlfriend Rachael, his best friend Kyle's crude but loyal friendship, his strained relationship with his overbearing mother dealing with his father's Alzheimer's, and his back pain.
Disruption
Dr. Ross tells Adam he has a malignant schwannoma neurofibrosarcoma on his spine - a rare cancer with a 50/50 survival rate. Adam is stunned and his controlled world shatters.
Resistance
Adam processes the diagnosis, tells Rachael and Kyle, meets his inexperienced therapist Katherine, and debates how to handle the situation. He begins chemotherapy while trying to maintain normalcy and control over his deteriorating situation.
Act II
ConfrontationFirst Threshold
Adam begins chemotherapy, actively choosing to fight the cancer. He enters the treatment center, shaves his head preemptively, and commits to the grueling process ahead.
Premise
Adam navigates cancer treatment with dark humor alongside his chemo buddies Alan and Mitch. Kyle uses Adam's cancer to pick up women. Adam bonds with Katherine through therapy sessions. The promise of the premise: a cancer comedy that finds humanity and humor in mortality.
Midpoint
Adam discovers Rachael has been cheating on him. Kyle reveals he saw her with another man. This false defeat compounds Adam's crisis - not only is his body betraying him, but so is his girlfriend. The stakes raise dramatically.
Opposition
Adam breaks up with Rachael, his treatment intensifies, he lashes out at those trying to help him, and his chemo buddy Alan dies. Adam's facade of control crumbles as he faces increasing physical deterioration and emotional isolation.
Collapse
Adam learns the chemotherapy hasn't worked and he needs immediate surgery with only a 50/50 chance of survival. His chemo buddy Mitch also dies. Death is no longer abstract - it's imminent and real.
Crisis
Adam has an emotional breakdown, finally allowing himself to feel fear and vulnerability. He pushes away Katherine when he discovers she's been using their sessions for her doctoral thesis, feeling betrayed by another person he trusted.
Act III
ResolutionSynthesis
Adam is prepped for surgery surrounded by Kyle and his mother. He confronts his mortality in the operating room. Post-surgery, he recovers, reconnects with Katherine romantically, and learns to live with uncertainty rather than control.







